人才隊伍
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高磊
研究生培養
培養碩士生6人，博士研究生6人。1人被評為北京協和醫學院優秀畢業生，1人被評為北京市優秀畢業生。
個人簡介
中國醫學科學院/北京協和醫學院病原生物學研究所副所長，課題組長。主要從事傳染病流行病學研究，重點探索適宜中國結核病高負擔國情的結核潛伏感染人群預防干預新技術和新方案。入選教育部新世紀優秀人才、北京市科技新星、協和新星等。國家傳染病標準專業委員會委員、中國防癆協會結核潛伏感染防治專業分會副主任委員、中國防癆協會標準化專業分會秘書長、第一批國家健康科普專家庫成員。中華結核和呼吸雜志、中國防癆雜志、BMC Infectious Diseases、PLOS Global Public Health、Chronic Diseases and Translational Medicine等學術期刊編委。作為第一作者或通訊作者在Lancet Infect Diseases，European Respiratory Journal等國際學術期刊發表SCI論文50余篇。獲中華預防醫學會科學技術一等獎、中國防癆協會科學技術一等獎、中華醫學科學技術二等獎、高等學校科學研究優秀成果獎自然科學類二等獎、中國醫學科學院“杰出貢獻獎”、中國醫學科學院-法國梅里埃研究院“青年科學家獎”等。
研究方向
結核病等重大傳染病的流行病學和精準干預研究
科研項目
1、傳染病防治科技重大項目，2017ZX10201302-009，結核潛伏感染干預治療效果研究 ，子課題負責人
2、傳染病防治科技重大項目，2017ZX10201302-00，肺結核人工智能影像診斷系統的優化升級，子課題負責人
3、中國醫學科學院醫學與健康科技創新工程，2019-I2M-2-005，農村中老年人群結核潛伏感染流行病學調查和干預研究隊列，課題負責人
4、傳染病防治科技重大項目，2017ZX10201302002，既往肺結核患者潛伏感染干預手段研究，子課題負責人
研究成果
1、Gao L, Lu W, Bai L, Wang X, Xu J, Catanzaro A, Cárdenas V, Li X, Yang Y, Du J, Sui H, Xia Y, Li M, Feng B, Li Z, Xin H, Zhao R, Liu J, Pan S, Shen F, He J, Yang S, Si H, Wang Y, Xu Z, Tan Y, Chen T, Xu W, Peng H, Wang Z, Zhu T, Zhou F, Liu H, Zhao Y, Cheng S, Jin Q; LATENTTB-NSTM study team. Latent tuberculosis infection in rural China: baseline results of a population-based, multicentre, prospective cohort study. Lancet Infect Dis. 2015 Mar;15(3):310-9.
2、Gao L, Li X, Liu J, Wang X, Lu W, Bai L, Xin H, Zhang H, Li H, Zhang Z, Ma Y, Li M, Feng B, Du J, Sui H, Zhao R, Su H, Pan S, Guan L, Shen F, He J, Yang S, Si H, Cheng X, Xu Z, Tan Y, Chen T, Xu W, Peng H, Wang Z, Zhu T, Chen X, Zhou X, Guan X, Jin Q; LATENTTB-NSTM study team. Incidence of active tuberculosis in individuals with latent tuberculosis infection in rural China: follow-up results of a population-based, multicentre, prospective cohort study. Lancet Infect Dis. 2017 Oct;17(10):1053-1061.
3、Zhang H, Xin H, Li X, Li H, Li M, Feng B, Gao L*. Reversion of QuantiFERON-TB Gold In-Tube test in individuals with and without prophylactic treatment for latent tuberculosis infection: A systematic review and meta-analysis. J Infect. 2018 Oct;77(4):276-282.
4、Zhang H, Xin H, Wang D, Pan S, Liu Z, Cao X, Wang J, Li X, Feng B, Li M, Yang Q, Zhang M, Jin Q, Gao L*. Serial testing of mycobacterium tuberculosis infection in Chinese village doctors by QuantiFERON-TB Gold Plus, QuantiFERON-TB Gold In-Tube and T-SPOT.TB. J Infect. 2019;78(4):305-10.
5、Xin H, Zhang H, Cao X, Li X, Li M, Feng B, Jin Q, Gao L*. Serum level of IL-8 is associated with reversion of QuantiFERON-TB gold in-tube tests. J Infect. 2019 Apr;78(4):292-298.
6、Gao L*, Bai L, Liu J, Lu W, Wang X, Li X, Du J, Chen X, Zhang H, Xin H, Sui H, Li H, Su H, He J, Pan S, Peng H, Xu Z, Catanzaro A, Evans TG, Zhang Z, Ma Y, Li M, Feng B, Li Z, Guan L, Shen F, Wang Z, Zhu T, Yang S, Si H, Wang Y, Tan Y, Chen T, Chen C, Xia Y, Cheng S, Xu W, Jin Q*; LATENTTB-NSTM study team. Annual risk of tuberculosis infection in rural China: a population-based prospective study. Eur Respir J. 2016;48(1):168-78.
7、Gao L*, Zhang H, Xin H, Liu J, Pan S, Li X, Guan L, Shen F, Liu Z, Wang D, Guan X, Yan J, Li H, Feng B, Cao X, Chen Y, Cui W, Zhang Z, Ma Y, Chen X, Zhou X, Jin Q*; LATENTTB-NSTM study team. Short-course regimens of rifapentine plus isoniazid to treat latent tuberculosis infection in older Chinese patients: a randomised controlled study. Eur Respir J. 2018 Dec 20;52(6):1801470.
8、Xin H, Cao X, Zhang H, Feng B, Du Y, Zhang B, Wang D, Liu Z, Guan L, Shen F, Guan X, Yan J, He Y, He Y, Quan Z, Pan S, Liu J, Jin Q, Gao L*. Protective efficacy of 6-week regimen for latent tuberculosis infection treatment in rural China: 5-year follow-up of a randomised controlled trial. Eur Respir J. 2022 Jul 7;60(1):2102359.
9、Xin H, Cao X, Zhang H, Liu J, Pan S, Li X, Guan L, Shen F, Liu Z, Wang D, Guan X, Yan J, Li H, Feng B, Zhang M, Yang Q, Jin Q, Gao L*; LATENTTB-NSTM study team. Dynamic changes of interferon gamma release assay results with latent tuberculosis infection treatment. Clin Microbiol Infect. 2020;26(11):p1555.e1-7.
10、Xin H, Zhang H, Liu J, Pan S, Li X, Cao X, Feng B, Guan L, Shen F, Liu Z, Wang D, Yan J, Zhang M, Yang Q, Jin Q, Gao L*. Tuberculosis infection among the elderly in 20,486 rural residents aged 50-70 years old in Zhongmu County, China. Clin Microbiol Infect. 2019;25(9):1120-6.
11、Zhang H, Xin H, Du Y, Cao X, Pan S, Liu J, Guan L, Shen F, Liu Z, Zhang B, Wang D, Feng B, Du J, Guan X, He Y, He Y, Zhang Z, Yan J, Jin Q, Gao L*; LATENTTB TRIAL2-NSTM study team. Tuberculosis preventive treatment among individuals with inactive tuberculosis suggested by untreated radiographic abnormalities: a community-based randomized controlled trial. Emerg Microbes Infect. 2023 Dec;12(1):e2169195.
12、Xin H, Zhang H, Yang S, Liu J, Lu Wei, Bai L, Cao X, Feng B, Jin Q, Gao L*. 5-year follow-up of active tuberculosis development from latent infection in rural China. Clin Infect Dis. 2020;70(5):947-50.
13、Li H, Xin H, Qian S, Li X, Zhang H, Li M, Feng B, Jin Q, Gao L*. The testing of tuberculosis infection among the adolescents born after booster Bacillus Calmette-Guérin vaccination was terminated in China: Subgroup analysis of a population-based cross-sectional study. Front Med. 2017;11(4):528-535.
14、Li X, Yang Y, Liu J, Zhou F, Cui W, Guan L, Shen F, Gao C, Li M, Jin Q*, Gao L*. Treatment outcomes of pulmonary tuberculosis in the past decade in the mainland of China: a meta-analysis. Front Med. 2013;7(3):354-66.
15、He Y, Cao X, Guo T, He Y, Du Y, Zhang H, Feng B, Du J, Zhang B, Wang K, Yan J, Wang D, Liu Z, Pan S, Xin H*, Gao L*. Serial testing of latent tuberculosis infection in patients with diabetes mellitus using interferon-gamma release assay, tuberculin skin test, and creation tuberculin skin test. Front. Public Health. 2022. 10:1025550.